Trucking Infrastructure

U.S. Trucking Routes and Interstate Freight Corridors

An enterprise reference of interstate trucking routes, major freight corridors, and commercial vehicle networks connecting distribution centers, manufacturing facilities, and ports across the continental United States.

48,000+
Interstate Highway Miles
41,518
National Highway Freight Network
900,000+
Registered Trucking Companies
11.8B
Annual Freight Tonnage

Major Interstate Trucking Corridors

The National Highway Freight Network designates primary interstate routes for commercial vehicle traffic. These corridors form the backbone of U.S. trucking operations, connecting metropolitan areas, manufacturing centers, and international trade gateways.

I-10East-West

I-10 Corridor

Santa Monica, CA → Jacksonville, FL
2,460 miles

Key Characteristics

  • Primary southern transcontinental route
  • Connects Los Angeles and Houston port complexes
  • Major manufacturing and distribution corridor
  • Significant NAFTA trade volume through Texas

Major Distribution Hubs

Los AngelesPhoenixEl PasoSan AntonioHoustonNew Orleans

States Served

CA → AZ → NM → TX → LA → MS → AL → FL
I-95North-South

I-95 Corridor

Miami, FL → Houlton, ME
1,920 miles

Key Characteristics

  • Highest-volume freight corridor in the U.S.
  • Serves major East Coast metropolitan markets
  • Critical for e-commerce distribution
  • Port connectivity from Miami to Boston

Major Distribution Hubs

MiamiJacksonvilleSavannahCharlotteRichmondBaltimorePhiladelphiaNew YorkBoston

States Served

FL → GA → SC → NC → VA → MD → DE → PA → NJ → NY → CT → RI → MA → NH → ME
I-80East-West

I-80 Corridor

San Francisco, CA → Teaneck, NJ
2,900 miles

Key Characteristics

  • Northern transcontinental freight route
  • Traverses industrial Midwest
  • Key automotive and manufacturing corridor
  • Winter weather challenges in mountain sections

Major Distribution Hubs

San Francisco/OaklandRenoSalt Lake CityOmahaChicagoClevelandNew York Metro

States Served

CA → NV → UT → WY → NE → IA → IL → IN → OH → PA → NJ
I-40East-West

I-40 Corridor

Barstow, CA → Wilmington, NC
2,555 miles

Key Characteristics

  • Historic Route 66 replacement corridor
  • Central transcontinental freight lane
  • Distribution hub connectivity across mid-latitudes
  • Year-round operational reliability

Major Distribution Hubs

Los Angeles BasinAlbuquerqueAmarilloOklahoma CityLittle RockMemphisNashvilleRaleigh

States Served

CA → AZ → NM → TX → OK → AR → TN → NC
I-35North-South

I-35 Corridor (NAFTA Highway)

Laredo, TX → Duluth, MN
1,568 miles

Key Characteristics

  • Primary U.S.-Mexico trade corridor
  • Connects border crossing to Midwest
  • High cross-border freight volume
  • Intermodal rail integration at Dallas and Kansas City

Major Distribution Hubs

LaredoSan AntonioAustinDallas-Fort WorthOklahoma CityKansas CityMinneapolis-St. Paul

States Served

TX → OK → KS → MO → IA → MN
I-5North-South

I-5 Corridor

San Diego, CA → Blaine, WA
1,381 miles

Key Characteristics

  • West Coast primary freight artery
  • Port of Los Angeles/Long Beach connectivity
  • Pacific Northwest distribution access
  • Agricultural freight from Central Valley

Major Distribution Hubs

San DiegoLos AngelesFresnoSacramentoPortlandSeattleTacoma

States Served

CA → OR → WA
I-75North-South

I-75 Corridor

Miami, FL → Sault Ste. Marie, MI
1,786 miles

Key Characteristics

  • Primary Southeast-to-Midwest freight artery
  • Automotive industry corridor (Detroit-Atlanta)
  • Florida agricultural and distribution freight
  • Connects major manufacturing centers

Major Distribution Hubs

MiamiTampaAtlantaChattanoogaKnoxvilleLexingtonCincinnatiToledoDetroit

States Served

FL → GA → TN → KY → OH → MI
I-70East-West

I-70 Corridor

Baltimore, MD → Cove Fort, UT
2,153 miles

Key Characteristics

  • Central East-West transcontinental route
  • Major Midwest manufacturing corridor
  • Denver distribution gateway
  • Heavy automotive and consumer goods traffic

Major Distribution Hubs

BaltimoreColumbusIndianapolisSt. LouisKansas CityDenver

States Served

MD → PA → WV → OH → IN → IL → MO → KS → CO → UT
I-20East-West

I-20 Corridor

Florence, SC → Kent, TX (I-10)
1,539 miles

Key Characteristics

  • Deep South freight corridor
  • Atlanta-Dallas connection
  • Automotive and manufacturing freight
  • Port of Charleston connectivity

Major Distribution Hubs

FlorenceColumbiaAtlantaBirminghamJacksonShreveportDallas-Fort Worth

States Served

SC → GA → AL → MS → LA → TX
I-90East-West

I-90 Corridor

Boston, MA → Seattle, WA
3,020 miles

Key Characteristics

  • Longest interstate highway in the U.S.
  • Northern tier transcontinental route
  • Agricultural freight from Great Plains
  • Chicago hub connectivity

Major Distribution Hubs

BostonBuffaloClevelandChicagoMadisonSioux FallsBillingsSpokaneSeattle

States Served

MA → NY → PA → OH → IN → IL → WI → MN → SD → WY → MT → ID → WA
I-94East-West

I-94 Corridor

Port Huron, MI → Billings, MT
1,585 miles

Key Characteristics

  • Upper Midwest freight corridor
  • Chicago-Detroit automotive lane
  • Minneapolis-St. Paul hub connection
  • Agricultural commodities from Northern Plains

Major Distribution Hubs

DetroitChicagoMilwaukeeMinneapolis-St. PaulFargoBismarckBillings

States Served

MI → IN → IL → WI → MN → ND → MT
I-85North-South

I-85 Corridor

Montgomery, AL → Petersburg, VA
666 miles

Key Characteristics

  • Southeast automotive corridor
  • Charlotte banking and distribution hub
  • Atlanta regional connectivity
  • Textile and manufacturing freight

Major Distribution Hubs

MontgomeryAtlantaGreenville-SpartanburgCharlotteGreensboroDurhamPetersburg

States Served

AL → GA → SC → NC → VA
I-65North-South

I-65 Corridor

Mobile, AL → Gary, IN
887 miles

Key Characteristics

  • Gulf-to-Midwest freight corridor
  • Automotive manufacturing lane
  • Nashville and Louisville hub access
  • Port of Mobile connectivity

Major Distribution Hubs

MobileMontgomeryBirminghamNashvilleLouisvilleIndianapolisGary/Chicago

States Served

AL → TN → KY → IN
I-15North-South

I-15 Corridor

San Diego, CA → Sweetgrass, MT
1,433 miles

Key Characteristics

  • Intermountain West primary corridor
  • Las Vegas distribution hub
  • Salt Lake City logistics gateway
  • Canada border crossing at Sweetgrass

Major Distribution Hubs

San DiegoLas VegasSalt Lake CityIdaho FallsButteGreat Falls

States Served

CA → NV → AZ → UT → ID → MT
I-81North-South

I-81 Corridor

Knoxville, TN → Watertown, NY
855 miles

Key Characteristics

  • Appalachian freight corridor
  • Shenandoah Valley distribution
  • East Coast alternative to I-95
  • Lower congestion north-south option

Major Distribution Hubs

KnoxvilleRoanokeHarrisonburgHarrisburgScrantonSyracuseWatertown

States Served

TN → VA → WV → MD → PA → NY
I-44East-West

I-44 Corridor

Texas (I-35) → St. Louis, MO
634 miles

Key Characteristics

  • Southwest to Midwest connector
  • Historic Route 66 segment
  • Oklahoma City distribution access
  • Tulsa energy sector freight

Major Distribution Hubs

Wichita FallsOklahoma CityTulsaJoplinSpringfieldSt. Louis

States Served

TX → OK → MO
I-55North-South

I-55 Corridor

LaPlace, LA → Chicago, IL
964 miles

Key Characteristics

  • Mississippi River parallel corridor
  • Memphis mega-hub connectivity
  • New Orleans port access
  • Agricultural and intermodal freight

Major Distribution Hubs

New OrleansJacksonMemphisSt. LouisSpringfieldChicago

States Served

LA → MS → TN → AR → MO → IL

Secondary and Regional Freight Corridors

Beyond the primary interstate highways, these corridors provide critical connectivity between regions, serve specialized industrial needs, and offer routing alternatives during congestion or seasonal disruptions.

I-77600 mi
Cleveland, OH – Columbia, SC
Appalachian north-south connector, automotive corridor
I-64940 mi
St. Louis, MO – Virginia Beach, VA
Ohio Valley corridor, Louisville-Hampton Roads freight
I-30367 mi
Dallas, TX – Little Rock, AR
Dallas-to-Memphis connector via Little Rock
I-26350 mi
Charleston, SC – Kingsport, TN
Port of Charleston inland access
I-57390 mi
Chicago, IL – Sikeston, MO
Chicago-to-Memphis alternate, agricultural freight
I-74420 mi
Cincinnati, OH – Davenport, IA
Indianapolis-Quad Cities corridor
I-29755 mi
Kansas City, MO – Canadian Border
Great Plains north-south, agricultural freight
I-24316 mi
Chattanooga, TN – Marion, IL
Southeast-to-Midwest connector via Nashville

Trucking Carrier Coverage

The U.S. trucking industry comprises national carriers with enterprise route networks, regional specialists, and independent owner-operators. Major carriers operate across interstate corridors with varying service levels and equipment specializations.

National LTL Carriers

Less-than-truckload carriers operating nationwide terminal networks for consolidated freight shipments.

FedEx Freight
Priority & Economy LTL
Old Dominion Freight Line
Regional/National LTL
XPO Logistics
LTL & Final Mile
Saia Inc.
Next-Day & Deferred LTL
ABF Freight System
LTL & Dedicated
Estes Express Lines
LTL & Volume
TForce Freight
LTL Services
R+L Carriers
LTL & Logistics

Major Truckload Carriers

Full truckload carriers offering dedicated fleet and over-the-road long-haul services.

J.B. Hunt Transport
Intermodal & Dedicated
Schneider National
Truckload & Intermodal
Werner Enterprises
Dedicated & OTR
Knight-Swift Transportation
Truckload & Logistics
Landstar System
Owner-Operator Network
Heartland Express
Short-Haul Truckload
Covenant Transportation
Refrigerated & Dedicated
U.S. Xpress
Truckload & Dedicated

Specialized Trucking

Carriers focused on specific freight types requiring specialized equipment or handling.

Prime Inc.
Refrigerated & Flatbed
C.R. England
Temperature-Controlled
Mercer Transportation
Flatbed & Heavy Haul
Anderson Trucking Service
Heavy Haul & Specialized
Kenan Advantage Group
Bulk & Tanker
Quality Distribution
Chemical & Bulk

Understanding U.S. Trucking Routes

Trucking routes in the United States form the most extensive and flexible component of the domestic freight network. Unlike rail or air cargo, trucking provides door-to-door service capability, making it the primary mode for final-mile delivery and regional distribution.

The interstate highway system, established in 1956, created standardized, high-capacity corridors that enable predictable transit times across continental distances. Modern freight corridors are designated under the National Highway Freight Network, which prioritizes infrastructure investment for commercial vehicle traffic.

Route Selection Factors

  • Distance and Transit Time: Direct routing versus hub-and-spoke models based on shipment urgency
  • Hours of Service Regulations: Driver rest requirements affecting multi-day routing
  • Toll and Fuel Costs: Economic optimization across alternative corridors
  • Weather and Seasonal Conditions: Mountain passes and winter routing considerations
  • Weight Restrictions: State-by-state variations in allowable gross vehicle weight

Fleet Equipment Reliability

Modern trucking fleets depend on electronic control modules, telematics systems, and emission control electronics. When ECM failures or sensor malfunctions sideline equipment, fleet operators increasingly rely on electronics repair technicians who specialize in specific boards rather than replacing entire modules—reducing both downtime and cost.